Helena Factor VII (10x1mL)

Factor VII (10x1mL)

Factor VII Deficient Substrate, 10 x 1 mL

Intended Use

The Factor Deficient Substrate Plasmas (II, V, VII, & X) are intended for the quantitative determination of the respective factor in patients suspected of having a congenital or acquired deficiency of this coagulation protein.

Summary

Numerous coagulation factors have been identified in the blood and are required for normal blood clotting. A deficiency of one or more of the factors may result in a notable hemorrhagic condition, the severity of which is governed by the degree of the deficiency. Deficiencies of the blood clotting factors may be congenital or acquired. The congenital deficiencies are in general single deficiency states while the acquired deficiencies may be multiple in nature and commonly associated with liver disease, vitamin K deficiency or the ingestion of coumarin type anticoagulant drugs, and defibrination secondary to intravascular clotting.

In 1935, Dr. Armond J. Quick developed the one-stage prothrombin time test. It is on the basis of this test that we are able to perform assays for Factors II, V, VII, and X activities by the incorporation of deficient substrate plasma.